Proton nuclear magnetic resonance spectroscopy showed that piroxicam sodium salt forms an inclusion complex with beta-cyclodextrin in aqueous solution. The 1:1 stoichiometry of the complex was determined by the continuous variation method. Significant nuclear Overhauser effects were observed between
✦ LIBER ✦
Qualitative analysis of the stability of the oxazine ring of various benzoxazine and pyridooxazine derivatives with proton nuclear magnetic resonance spectroscopy
✍ Scribed by Gerard P. Moloney; David J. Craik; Magdy N. Iskander
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 570 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0022-3549
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## Abstract The possible mechanisms for the chiral recognition of 2‐(__R__)‐__N__‐[1‐(6‐aminopyridin‐2‐ylmethyl)piperidin‐4‐yl]‐2‐[(1__R__)‐3,3‐difluorocyclopentyl]‐2‐hydroxy‐2‐phenylacetamide (RR‐M3), and its enantiomer (SS‐M3) with octakis(2,3‐di‐__O__‐acetyl‐6‐sulfo)‐γ‐cyclodextrin (ODAS‐γ‐CD) a