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Qualitative Alterations of Cytochrome P-450 in Mouse Liver Microsomes after Administration of Acrylamide and Methylmethacrylate

✍ Scribed by Nilsen, Odd. G. ;Toftgård, Rune ;Ingelman-Sundberg, Magnus ;Gustafsson, Jan-Åke

Book ID
114799541
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
594 KB
Volume
43
Category
Article
ISSN
0001-6683

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✍ Marker, Elizabeth K. ;Kulkarni, Arun P. 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 802 KB

Enzymatic denitrification of 2-nitropropane (2NP) was investigated in an NADPH-dependent hepatic microsomal system from male CD1 mice. The involvement of cytochrome P-450 (P-450) as the catalyst in 2NP denitrification was revealed by the induction of nitrite-releasing activity following phenobarbita