Cytochrome P-450βMediated denitrificatio
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Marker, Elizabeth K. ;Kulkarni, Arun P.
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Article
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1986
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John Wiley and Sons
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English
β 802 KB
Enzymatic denitrification of 2-nitropropane (2NP) was investigated in an NADPH-dependent hepatic microsomal system from male CD1 mice. The involvement of cytochrome P-450 (P-450) as the catalyst in 2NP denitrification was revealed by the induction of nitrite-releasing activity following phenobarbita