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QSAR studies on imidazothienopyrazines as IKK-β inhibitors: from 2D to 3D

✍ Scribed by Wei Long; Peixun Liu; Xinru Li; Yang Xu; Jie Yu; Shitang Ma; Lingling Yu; Zhongmei Zou


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
329 KB
Volume
23
Category
Article
ISSN
0886-9383

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## Abstract The ligand‐based three‐dimensional quantitative structure‐activity relationship (3D‐QSAR) for 82 inhibitors of 25‐dehydro‐1__α__‐hydroxyvitamin D~3~‐26,23‐lactone analogs has been studied by using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices