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QS295. Cyclin E Deregulation Is an Early Event in the Development of Breast Cancer

✍ Scribed by I. Bedrosian; A. Shaye; A. Sahin; Q. Hao; K. Hunt; K. Keyomarsi

Book ID
116705116
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
89 KB
Volume
151
Category
Article
ISSN
0022-4804

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## Abstract In this review, we focus on pathways intersecting through p53 and cyclin E, highlighting how oncogenic effects of cyclin E deregulation, especially overexpression of shortened or low molecular weight (LMW) forms of cyclin E protein, are amplified by loss of regulatory control through p5