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QS239. Adventitial Fibroblasts in Thoracic Aortic Aneurysm and Dissection (TAAD)

✍ Scribed by Jeong S. Yoon; Lin Zhang; Ying H. Shen; Monique Criddell; Scott A. LeMaire; Dianna M. Milewicz; Joseph S. Coselli; Xing Li Wang

Book ID: 116704011
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 40 KB
Volume: 144
Category: Article
ISSN: 0022-4804
DOI: 10.1016/j.jss.2007.12.486

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## Abstract Regulation of fibronectin (FN) by Platelet‐derived Growth Factor‐BB (PDGF‐BB) and Insulin‐like Growth Factor‐I (IGF‐I) in cultured rat thoracic aortic adventitial fibroblasts were examined. PDGF‐BB enhances FN mRNA levels in a time and concentration‐dependent fashion. The effect of IGF‐