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Role of aggregated medin in the pathogenesis of thoracic aortic aneurysm and dissection

✍ Scribed by Peng, Siwei; Larsson, Annika; Wassberg, Erik; Gerwins, Pär; Thelin, Stefan; Fu, Xin; Westermark, Per


Book ID
109886202
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
413 KB
Volume
87
Category
Article
ISSN
0023-6837

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Genetic basis of thoracic aortic aneurys
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## Abstract Ascending thoracic aortic aneurysms leading to type A dissections (TAAD) can occur in association with a genetic syndrome, such as Marfan syndrome (MFS), or as an autosomal dominant disorder in the absence of syndromic features, termed familial TAAD. Familial TAAD demonstrates genetic h