Pyrrolobenzoxazepinone Derivatives as Non-Nucleoside HIV-1 RT Inhibitors: Further Structure−Activity Relationship Studies and Identification of More Potent Broad-Spectrum HIV-1 RT Inhibitors with Antiviral Activity
✍ Scribed by Campiani, Giuseppe; Morelli, Elena; Fabbrini, Monica; Nacci, Vito; Greco, Giovanni; Novellino, Ettore; Ramunno, Anna; Maga, Giovanni; Spadari, Silvio; Caliendo, Giuseppe; Bergamini, Alberto; Faggioli, Emanuela; Uccella, Ilaria; Bolacchi, Francesca; Marini, Stefano; Coletta, Massimiliano; Nacca, Angelo; Caccia, Silvio
- Book ID
- 121382086
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 240 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0022-2623
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## Abstract Arylthio isopropyl pyridinylmethylpyrrolemethanols (AThPs) have been recently reported as a new class of human immunodeficiency virus type 1 (HIV‐1) reverse transcriptase (RT) inhibitors acting at the non‐nucleoside binding site (NNBS) of this enzyme. Docking experiments of the potent i