Pyrrole, furan, and thiophene oxamates as potential antiallergy agents
β Scribed by Fredda H. Briggs; William T. Pelletier; C. Dewitt Blanton Jr.
- Book ID
- 102405915
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 346 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
β¦ Synopsis
Nine heterocyclic oxamic acid derivatives were synthesized and tested in the rat passive cutaneous anaphylactic assay as potential antiallergy agents. Some compounds also were tested for their effects on cholesterol-lipoprotein levels and for diuretic, antidiabetic, and antifertility activities in rats.
π SIMILAR VOLUMES
## Abstract Sulfamic acid has been utilized for the first time as an efficient and reusable catalytic system for the synthesis of heteroaromatics such as pyrrole, furan, and thiophene derivatives from 1,4βdiketones. This new procedure offers significant improvements in the reaction rates and yields