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Pyrimidine acyclic nucleosides. 1-[(2-Hydroxyethoxy)methyl]pyrimidines as candidate antivirals

โœ Scribed by Kelley, James L.; Kelsey, John E.; Hall, William R.; Krochmal, Mark P.; Schaeffer, Howard J.


Book ID
124056310
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
617 KB
Volume
24
Category
Article
ISSN
0022-2623

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ChemInform Abstract: Acyclic Analogues o
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Acyclic Analogues of Pyrimidine Nucleosides. Synthesis of 1-(2-Hydroxyethoxy)methyl-and 1-(4-Hydroxybutyl)-5-amino Derivatives of Uracil. -Reaction of 5-aminouracil derivatives (I) with 4-bromobutyl acetate (II) or chloromethoxyethyl benzoate (V) followed by deacylation affords the title uracil der