𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Pyrimethamine in prevention of relapses of meningeal leukemia. Report of two cases

✍ Scribed by Jerzy Armata; Romana Cyklis; Wlodzimierz Borkowski

Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
242 KB
Volume
42
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.

✦ Synopsis

Relapses of meningeal leukemia occurred in two children during hematologic remission of acute lymphoblastic leukemia. Treatment of CNS leukemia consisted of radiotherapy and repeated intrathecal injections of methotrexate and cytosine arabinoside. Intrathecal installations of the drugs were accompanied with increasing neurological side effects which seemed to be lifethreatening. To avoid them, repeated courses of pyrimethamine were introduced. No further relapse of meningeal leukemia occurred after pyrimethamine. Hematologic remissions in both children have lasted for over 7 years. All therapy was stopped 16 months ago.

πŸ“œ SIMILAR VOLUMES

Congenital leukemia: Report of two cases
Congenital leukemia: Report of two cases
✍ Dr. J. Philip McCoy Jr.; Susan F. Travis; Linda Blumstein; Peggy B. Birdsall; Ka πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 396 KB
Acute lymphoblastic leukemia in Noonan s
Acute lymphoblastic leukemia in Noonan syndrome: Report of two cases
✍ Piombo, Margherita ;Rosanda, Cristina ;Pasino, Mirella ;Marasini, Maurizio ;Cerr πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 339 KB

## Abstract Only two cases of Noonan Syndrome (NS) associated with tumor have previously been reported. The authors describe two new cases of NS with acute lymphoblastic leukemia (ALL), which were part of a series of 370 consecutive ALL untreated patients. Β© 1993 Wiley‐Liss, Inc.

Recognition of leukemia in skeletal rema
Recognition of leukemia in skeletal remains: Report and comparison of two cases
✍ Rothschild, B. M.; Hershkovitz, I.; Dutour, O.; Latimer, B.; Rothschild, C.; Jel πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 634 KB

Recognition of disease in the archeologic record is facilitated by characterization of the skeletal impact of documented (in life) disease. The present study describes the osteological manifestations of leukemia as identified in the skeletons of two individuals diagnosed during life: a 3-year-old bl

Prevention of Rh sensitization in the co
Prevention of Rh sensitization in the context of trauma: Two case reports
✍ Jochewed B. Werch πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 74 KB

## Abstract ## Background: Transfusion of D+ red blood cells (RBCs) to Dβˆ’ recipients can be accidental or necessary due to Dβˆ’ RBC shortage. Alloimmunization can complicate future transfusions; implications for women of childbearing age are compounded by possible hemolytic disease of the fetus and