A patient with acute myelofibrosis developed acute leukemia during the course of her disease. Light microscopic examination showed that the cells were lymphoblasts. The presence of terminal deoxynucleotidyl transferase and Tand B-lymphocyte markers suggested that the malignancy was of immature lymph
Acute lymphoblastic leukemia in Noonan syndrome: Report of two cases
β Scribed by Piombo, Margherita ;Rosanda, Cristina ;Pasino, Mirella ;Marasini, Maurizio ;Cerruti, Paola ;Comelli, Adele
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 339 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0098-1532
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β¦ Synopsis
Abstract
Only two cases of Noonan Syndrome (NS) associated with tumor have previously been reported. The authors describe two new cases of NS with acute lymphoblastic leukemia (ALL), which were part of a series of 370 consecutive ALL untreated patients. Β© 1993 WileyβLiss, Inc.
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