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Pyridopyrimidines. 8. A novel ring opening during the acylation of 6-amino-1,3-dimethyluracil

โœ Scribed by Anderson, Gary L.; Broom, Arthur D.


Book ID
121352684
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
384 KB
Volume
42
Category
Article
ISSN
0022-3263

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The regiosetective ring-opening reaction of a-methyl-B-propiolactone with 3,3-ethytenedioxybutytmagnesiwn bromide in the presence of copper(I) cataZyst afforded 2-methyl-6-oxoheptanoic acid, which was easily converted into IEI-3,7-dimethyl-2-octene-I,&dial in good yield.

ChemInform Abstract: Ring-Ring Interconv