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Pyrido[2,3-d]pyrimidines from Malonaldehydes 1

โœ Scribed by Bernetti, Raffaele; Mancini, Franco; Price, Charles C.


Book ID
120412936
Publisher
American Chemical Society
Year
1962
Tongue
English
Weight
358 KB
Volume
27
Category
Article
ISSN
0022-3263

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Synthesis of pyrido[2,3-d]pyrimidines fr
โœ Francisco Perandones; Josรฉ L. Soto ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 568 KB

## Abstract 2โ€Methoxyโ€4โ€aminoโ€5โ€pyrimidinecarbaldehyde (2a) as well as its 6โ€methyl 2b and 6โ€phenyl derivatives 2c were prepared by reduction of the corresponding aminopyrimidinecarbonitriles 1. Catalytic hydrogenation of 1a, 1b gives 5โ€hydroxymethylpyrimidines 3a, 3b; under the same conditions 1c