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Pyridazines. XLV . on the mechanism of an unusual 1,2-diazine → 1,2-diazole ring contraction

✍ Scribed by Gottfried Heinisch; Thierry Huber; Christina Langer; Walter Gössler; Gert Kollenz


Book ID
112129333
Publisher
Journal of Heterocyclic Chemistry
Year
1989
Tongue
English
Weight
237 KB
Volume
26
Category
Article
ISSN
0022-152X

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Studies on an unexpected reaction involving a reductive cleavage of the pyridazine moiety of a tricyclic heterocycle are described. Structure assignments for the products obtained from the reductive cleavage were made using physicochemical methods. The pro drug' (TCN-P, fi) of 6-amino-4-N-methyl-8-(