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Pyrazolodiazepines. 1,3-(and 2,3-) Dialkyl-4,6-dihydro-8-arylpyrazolo[4,3-e][1,4]diazepin-5-ones as antianxiety agents

โœ Scribed by DeWald, Horace A.; Nordin, Ivan C.; L'Italien, Yvon J.; Parcell, Robert F.

Book ID
121421503
Publisher
American Chemical Society
Year
1973
Tongue
English
Weight
858 KB
Volume
16
Category
Article
ISSN
0022-2623

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A facile approach to pyrazolo [4,3-e][1,4] diazepin-5,8-diones andpyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepin-5,10-diones is reported. Strategy involved the utility of ฮฑ-amino acid as a three-atom segment in the construction of diazepine skeleton on the preformed pyrazole ring.