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Pyrazolo[3,4-d]pyrimidine ribonucleosides as anticoccidials. 1. Synthesis and activity of some nucleosides of purines and 4-(alkylthio)pyrazolo[3,4-d]pyrimidines

โœ Scribed by Krenitsky, Thomas A.; Rideout, Janet L.; Koszalka, George W.; Inmon, Rosetta B.; Chao, Esther Y.; Elion, Gertrude B.; Latter, Victoria S.; Williams, Raymond B.

Book ID
115450563
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
573 KB
Volume
25
Category
Article
ISSN
0022-2623

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A convenient synthesis of pyrazolo[3,4-d
A convenient synthesis of pyrazolo[3,4-d]pyrimidine-4,6-dione and pyrazolo[4,3-d]pyrimidine-5,7-dione derivatives
โœ M. El Haddad; M. Soukri; S. Lazar; A. Bennamara; G. Guillaumet; M. Akssira ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 470 KB

## Abstract Pyrazoloโ€[3,4โ€__d__]pyrimidineโ€4,6โ€diones **5** and pyrazolo[4,3โ€__d__]pyrimidineโ€5,7โ€diones **7** were synthesized by Curtius rearrangement of pyrazolic monoโ€esters **2** and **3** followed by heteroโ€cyclization __via__ the ureas derivatives **4** and **6** under alkaline conditions.