PX-478, an inhibitor of hypoxia-inducibl
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Sanjeewani T. Palayoor; James B. Mitchell; David Cerna; William DeGraff; Molykut
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Article
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2008
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John Wiley and Sons
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French
β 368 KB
## Abstract Overexpression of hypoxiaβinducible factorβ1Ξ± (HIFβ1Ξ±) in human tumors is associated with poor prognosis and poor outcome to radiation therapy. Inhibition of HIFβ1Ξ± is considered as a promising approach in cancer therapy. The purpose of this study was to test the efficacy of a novel HIF