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Putative Role of Functional Interferon Regulatory Factor 5 (IRF5) Polymorphism in Rheumatoid Arthritis in a Korean Population

✍ Scribed by Kim, Yun Jung; Park, Jeong Ha; Kim, Il; Kim, Ji On; Bae, Joon Seol; Shin, Hyoung Doo; Bae, Sang-Cheol


Book ID
111688780
Publisher
Journal of Rheumatology Publishing Company
Year
2008
Tongue
English
Weight
437 KB
Volume
35
Category
Article
ISSN
0315-162X

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## Abstract ## Objective Recent findings suggest that interferon regulatory factor 5 (IRF‐5) may play a crucial role in several cellular processes, including the transcription of genes for inflammatory cytokines. Two genetic variants of the __IRF5__ gene (rs2004640 in exon 1 and rs2280714 in the 3