## Abstract ## Objectives/Hypothesis: Interferon regulatory factor 6 (__IRF6__), the gene that causes van der Woude syndrome (VWS), is a candidate gene for nonsyndromic cleft lip with or without cleft palate (NSCLP) because a number of studies have supported an association between NSCLP and single
โฆ LIBER โฆ
Interferon regulatory factor (IRF)-6 820 (G>A) polymorphism is not assiciated with nonsyndromic cleft lip and/or palate in korean population
โ Scribed by Hyun Soo Park; Kun Woo Kim; Cha-Hui Lee; Soon-Sup Shim; Joong Shin Park; Jong Kwan Jun
- Book ID
- 113431771
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 58 KB
- Volume
- 195
- Category
- Article
- ISSN
- 1097-6868
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## Abstract **INTRODUCTION:** Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common of all birth defects. NSCL/P has a multifactorial etiology that includes both genetic and environmental factors. The __IRF6__ gene and three further susceptibility loci at 8q24, 10q2