✦ LIBER ✦

Purification of labelled retinoic acid and characterization of a major impurity

✍ Scribed by R. M. McKenzie; M. L. McGregor; E. C. Nelson

Publisher: John Wiley and Sons
Year: 1978
Tongue: French
Weight: 502 KB
Volume: 15
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580150133

No coin nor oath required. For personal study only.

✦ Synopsis

All-trans-[15-"C] r e t i n o i c acid and all-trans-[l0,11-'H~]retinoic acid were p u r i f i e d by thin-layer chromatography (TLC) and high performance l i q u i d chromatography (HPLC). r e t i n o i c a c i d , was i s o l a t e d , characterized and t e n t a t i v e l y i d e n t i f i e d as an epoxide of r e t i n o i c acid.

A major impurity, present i n both "C-and 'H-labelled 'To whom correspondence should be addressed.

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