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Purification, characterization, substrate and inhibitor specificity of adenosine kinase from several Eimeria species

✍ Scribed by Richard L. Miller; David L. Adamczyk; Janet L. Rideout; Thomas A. Krenitsky


Book ID
113259745
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
754 KB
Volume
6
Category
Article
ISSN
0166-6851

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Damage to DNA can result in strand breaks with 58-hydroxyl and 38-phosphate termini. Before DNA polymerases and ligases can rejoin the broken strands, such termini have to be restored to 58-phosphate and 38-hydroxyl groups. Polydeoxynucleotide kinase is an enzyme that may fulfil this function. We ha