A homology model for the human theta-cla
✍
J.U. Flanagan; J. Rossjohn; M.W. Parker; P.G. Board; G. Chelvanayagam
📂
Article
📅
1998
🏛
John Wiley and Sons
🌐
English
⚖ 181 KB
A manual threading approach is used to model the human glutathione transferase T1-1 based on the coordinates of the related Theta class enzyme T2-2. The low level of sequence identity (about 20%), found in the C-terminal extension in conjunction with a relative deletion of about five residues makes