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Purification and properties of immunotoxins containing one vs. two deglycosylated ricin A chains

โœ Scribed by Victor Ghetie; Eric Swindell; Jonathan W. Uhr; Ellen S. Vitetta

Book ID
118902764
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
428 KB
Volume
166
Category
Article
ISSN
0022-1759

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โœ Edward J. Wawrzynczak; Alan J. Cumber; Raymond V. Henry; Geoffrey D. Parnell ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 718 KB

lmmunotoxins were constructed by attaching native ricin A chain, ricin A, chain and recombinant r i c h A chain to the mouse monoclonal IgG,, antibody Fib75 by means of a disulphide linkage using the hetero-bifunctional cross-linker SPDP. The Fib75 immunotoxins were of similar composition and exerte