We previously reported that the human Y' bile acid binder, which has higher bile acid binding affinities than rat Y' binders (3a-hydroxysteroid dehydrogenases), has dihydrodiol dehydrogenase activity and is different from 3a-hydroxyeteroid dehydrogenases. In this study, 3a-hydmxyeteroid dehydrogenas
Purification and Properties of 3α-Hydroxysteroid Dehydrogenase and 3-Keto-5β-steroid-Δ4-dehydrogenase
✍ Scribed by XIAOLIN GAO; JIANGUO LIU; GAOXIANG LI
- Book ID
- 111394267
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 475 KB
- Volume
- 864
- Category
- Article
- ISSN
- 0890-6564
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The activity of 3 beta-hydroxysteroid dehydrogenase delta 4-5 isomerase (3 beta-HSD) was assayed in various tissues microdissected from the freeze-dried human skin of 13 subjects. The sebaceous gland possessed the highest activity of 3 beta-HSD in the skin, while the apocrine sweat gland showed only
## Abstract Little information is available for neurosteroidogenesis in the central nervous system (CNS) of lower vertebrates. Therefore, in the present study, we examined the enzymatic activity and localization of 3β‐hydroxysteroid dehydrogenase/Δ^5^‐Δ^4^‐isomerase (3βHSD), a key steroidogenic enz