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Purification and characterization of transcribed RNAs using gel filtration chromatography

✍ Scribed by McKenna, Sean A; Kim, Insil; Puglisi, Elisabetta Viani; Lindhout, Darrin A; Aitken, Colin Echeverría; Marshall, R Andrew; Puglisi, Joseph D

Book ID
109946402
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
244 KB
Volume
2
Category
Article
ISSN
1750-2799

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## Abstract ## Background Adenoviral vectors are used extensively in human gene therapy trials and in vaccine development. Large‐scale GMP production requires a downstream purification process, and liquid chromatography is emerging as the most powerful mode of purification, enabling the production