Purification and Characterization of NF-R2 that Regulates the Expression of the Human Multidrug Resistance (MDR1) Gene
β Scribed by Takatori, Toshiro ;Ogura, Mitsuo ;Tsuruo, Takashi
- Book ID
- 108580771
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1993
- Tongue
- English
- Weight
- 386 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0910-5050
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π SIMILAR VOLUMES
The human multidrug resistance protein 2 (MRP2), also termed as the canalicular multispecific organic anion transporter (cMOAT), is a member of the adenosine triphosphatebinding cassette transporter superfamily. In the liver, MRP2 mediates the multispecific efflux of various types of organic anions,
## Abstract ## BACKGROUND The Pβglyprotein (Pβgp), which is a membrane channel encoded by the __MDR1__ gene, represents a possible explanation for multidrug resistance in human hepatoblastoma (HB). Pβgp shows upβregulation in tumor cells after chemotherapy; however, to date, its exact role in HB h