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Purification and characterization of a microsomal cytochrome P-450 with high activity of coumarin 7-hydroxylase from mouse lives

✍ Scribed by Pekka KAIPAINEN; Daniel W. NEBERT; Matti A. LANG

Book ID
115122747
Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
722 KB
Volume
144
Category
Article
ISSN
1432-1327

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High expression of cytochrome P450 2a-5
High expression of cytochrome P450 2a-5 (coumarin 7-hydroxylase) in mouse hepatomas
✍ Valery Kobliakov; Ludmila Kulikova; Dimitri Samoilov; Matti A. Lang πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 421 KB

## Abstract A high level of Cyp2a‐5 was found in spontaneous and transplanted mouse hepatomas compared with normal liver. Increased expression of Cyp2a‐5 was associated with an increase in coumarin 7‐hydroxylation, a marker activity of Cyp2a‐5, and the corresponding mRNA, suggesting that regulation