Pulse cyclophosphamide therapy in Wegener's granulomatosis: a pilot study
β Scribed by A. A. DROSOS; L. I. SAKKAS; A. GOUSSIA; K. C. SIAMOPOULOS; H. M. MOUTSOPOULOS
- Book ID
- 114742273
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 246 KB
- Volume
- 232
- Category
- Article
- ISSN
- 0954-6820
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## Summary The introduction of cyclophosphamide (CyP) as a treatment for Wegener's granulomatosis (WG) and microscopic polyangiitis (MPA) has been among the most significant contributions in vasculitis. Prior to the introduction of CyP, WG was a uniformly fatal disease, with mortality occurring wit
## Abstract ## Objective Standard treatment for severe granulomatosis with polyangiitis (Wegener's) (GPA) is daily oral cyclophosphamide (CYC), a cytotoxic agent associated with ovarian failure. In this study, we assessed the rate of diminished ovarian reserve in women with GPA who received CYC ve