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Pulmonary pharmacokinetics and safety of nebulized duramycin in healthy male volunteers

✍ Scribed by Ilka Steiner; Peter Errhalt; Klaus Kubesch; Marianne Hubner; Marion Holy; Martin Bauer; Markus Müller; Sabine Hinterberger; Rudolf Widmann; Daniel Mascher; Michael Freissmuth; Meinhard Kneussl

Book ID
105876794
Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
265 KB
Volume
378
Category
Article
ISSN
0028-1298

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✍ Harri Kanerva; Olavi Kilkku; Esa Heinonen; Antti Helminen; Juha Rouru; Simo Tarp 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 201 KB 👁 2 views

The pharmacokinetics and tolerability of a new putative non-benzodiazepine type anxiolytic compound deramciclane was studied in two consecutive studies. An open dose-escalation design was used to study doses from 0.2 to 50 mg in 18 healthy male volunteers. In the second study doses from 50 to 150 mg