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Safety, tolerability and pharmacokinetics of higher-dose mizoribine in healthy male volunteers

✍ Scribed by Daria Stypinski; Mohammad Obaidi; Michelle Combs; Meg Weber; Adrian J. Stewart; Hiroaki Ishikawa


Book ID
108641723
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
226 KB
Volume
63
Category
Article
ISSN
0306-5251

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✍ Harri Kanerva; Olavi Kilkku; Esa Heinonen; Antti Helminen; Juha Rouru; Simo Tarp πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 201 KB πŸ‘ 2 views

The pharmacokinetics and tolerability of a new putative non-benzodiazepine type anxiolytic compound deramciclane was studied in two consecutive studies. An open dose-escalation design was used to study doses from 0.2 to 50 mg in 18 healthy male volunteers. In the second study doses from 50 to 150 mg