✦ LIBER ✦

Pulmonary metastasectomy for soft tissue sarcomas: Is it justified?

✍ Scribed by Dr. Daniel B. Frost

Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 489 KB
Volume: 59
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930590208

No coin nor oath required. For personal study only.

✦ Synopsis

The role of pulmonary metastasectomy for metastatic soft tissue sarcomas is examined by reviewing the recent (1978-1994) English language literature. There are no prospective studies that contain an appropriate control group, and only one retrospective study contains a matched control group. In those few studies that provide greater than 5-year survival data, the survival curve still has a steep slope and few patients are alive at 7 years. In most studies only one or two patients are at risk at 5 years or more. Projected survival is therefore statistically questionable. It is currently impossible to know what is the impact of the surgical procedure over and above the natural history (biology) of the tumor. A randomized, prospective study, as suggested a decade ago, is still needed. While there may be some merit to pulmonary metastasectomy in highly selected patients, aggressive pulmonary metastasectomy does not seem justified by the available data.

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