Pulmonary collectins in innate immunity of the lung
β Scribed by Yoshio Kuroki; Motoko Takahashi; Chiaki Nishitani
- Book ID
- 109041524
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 280 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1462-5814
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Collectins, present in plasma and on mucosal surfaces, are humoral molecules of the innate immune system. They were discovered a hundred years ago in 1906 as the first association of an animal lectin with the immune system. They are a family of calciumβdependent lectins that recognize p
The two lung surfactant collectins, surfactant protein (SP)-A and SP-D, are involved in host defence against infectious and allergenic agents via enhancement of killing and clearance by macrophages and neutrophils. Recent gene-knockout, protein engineering and physiological studies have emphasised t