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PTH/PTHrP Receptor in Early Development and Indian Hedgehog--Regulated Bone Growth

✍ Scribed by Lanske, B.; Karaplis, A. C.; Lee, K.; Luz, A.; Vortkamp, A.; Pirro, A.; Karperien, M.; Defize, L. H. K.; Ho, C.; Mulligan, R. C.; Abou-Samra, A.-B.; J ppner, H.; Segre, G. V.; Kronenberg, H. M.


Book ID
121156563
Publisher
American Association for the Advancement of Science
Year
1996
Tongue
English
Weight
632 KB
Volume
273
Category
Article
ISSN
0036-8075

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## Abstract Normal endochondral bone development requires the coordination of chondrocyte proliferation and differentiation. Indian hedgehog (Ihh) is a morphogen produced by chondrocytes in the early stage of terminal differentiation and plays several key roles in this process. Ihh regulates growth