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PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells

✍ Scribed by Zhao, Hong; Dupont, Joelle; Yakar, Shoshana; Karas, Michael; LeRoith, Derek

Book ID: 110068243
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 350 KB
Volume: 23
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1207162

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## Abstract The purpose of these experiments was to assess the synergistic activity of silibinin with chemotherapy agents in clinical use against prostate cancer. Silybin‐phytosome, a commercially available formulation containing silibinin, has recently been studied in a phase I clinical trial. The