Trichostatin a inhibits proliferation, induces apoptosis and cell cycle arrest in HeLa cells
β Scribed by Zhou-min Xu; Yi-qun Wang; Qi Mei; Jian Chen; Jia Du; Yan Wei; Ying-chun Xu
- Book ID
- 107466822
- Publisher
- Chinese Anti-Cancer Association
- Year
- 2006
- Tongue
- English
- Weight
- 321 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1000-9604
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Remodeling of the chromatin template by inhibition of HDAC activities represents a potential transcriptional therapy for neoplastic disease. A number of HDAC inhibitors that modulate __in vitro__ cell growth and differentiation have been developed. We analyzed the effects of TSA, a spec
## Abstract We investigated the in vitro effects of pyrogallol on cell growth, cell cycle regulation, and apoptosis in HeLa cells. Pyrogallol inhibited the growth of HeLa cells with an IC~50~ of approximately 45 Β΅M. Pyrogallol induced arrest during all phases of the cell cycle and also very efficie