Psychosocial issues in young-onset Parkinson's disease: Current research and challenges
β Scribed by Susan M. Calne; Sarah C. Lidstone; Ajit Kumar
- Book ID
- 116820381
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 145 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1353-8020
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## Abstract The effect of Parkinson's disease (PD) on young patients' lives is likely to differ from that in older patients. For this study, 75 patients with onset of PD before the age of 50 and 66 patients with later onset completed a booklet of questionnaires on demographic and clinical variables
hand. Contralateral involvement emerged after several months. Examination showed parkinsonian posture, rigidity, generalized bradykinesia, and resting tremor of both hands, more prominent on the right. These symptoms were levodoparesponsive but dyskinesias appeared after 1 year. He died of cardiac d
## Abstract Mutations of __PLA2G6__ gene have been lately proposed to be the causative gene for PARK14 in patients with autosomal recessive youngβonset parkinsonism (YOPD). The role of __PLA2G6__ mutations as a risk factor for Parkinson's disease is not clear. To study the __PLA2G6__ mutations in P