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Psychiatric symptoms and CAG expansion in Huntington's disease

✍ Scribed by Weigell-Weber, Maike; Schmid, Werner; Spiegel, Roland


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
27 KB
Volume
67
Category
Article
ISSN
0148-7299
DOI
10.1002/(sici)1096-8628(19960216)67:1<53::aid-ajmg9>3.0.co;2-t

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In several neurodegenerative diseases, anticipation or increase in disease severity in succeeding generations within families correlates with expansions of an intragenic CAG/CTG repeat sequence above the normal range through the generations of a pedigree. Some kindreds of familial Parkinson's diseas