The pharmacokinetics of 8-MOP were studied in six dogs following intravenous administration of 2 mg kg-'. In most animals a bi-exponential decline of the plasma level profile was observed. The calculated pharmacokinetic parameters varied considerably between the different dogs. The mean half-lives o
Psoralens and serendipity: Aspects of the genetic toxicology of 8-methoxypsoralen
β Scribed by Bridges, Bryn A.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1983
- Weight
- 711 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0192-2521
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## Abstract This article traces the development of the field of mutagenesis and its metamorphosis into the research area we now call genetic toxicology. In 1969, this transitional event led to the founding of the Environmental Mutagen Society (EMS). The charter of this new Society was to βencourage