## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
✦ LIBER ✦
Pseudomonas aeruginosaNfsB and nitro-CBI-DEI – a promising enzyme/prodrug combination for gene directed enzyme prodrug therapy
✍ Scribed by Laura K Green, Sophie P Syddall, Kendall M Carlin, Glenn D Bell…
- Book ID
- 120688455
- Publisher
- BioMed Central
- Year
- 2013
- Tongue
- English
- Weight
- 256 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1476-4598
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## Abstract ## Background Gene‐directed enzyme prodrug therapy (GDEPT) based on the __E. coli__ enzyme purine nucleoside phosphorylase (PNP) represents a new approach for treating slow growing tumours like prostate cancer (PCa). Expressed enzyme converts a systemically administered prodrug, fludar