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Synthesis and Evaluation of Nitroheterocyclic Carbamate Prodrugs for Use with Nitroreductase-Mediated Gene-Directed Enzyme Prodrug Therapy

โœ Scribed by Hay, Michael P.; Anderson, Robert F.; Ferry, Dianne M.; Wilson, William R.; Denny, William A.


Book ID
121713866
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
209 KB
Volume
46
Category
Article
ISSN
0022-2623

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โœ Jolanda J. de Poorter; Tanja C. A. Tolboom; Martijn J. W. E. Rabelink; Elsbet Pi ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 157 KB

## Background: Loosening is a major complication in prosthesis surgery. to stabilize loosened orthopedic implants, the interface tissue surrounding the implant must be removed. as an alternative to manual removal, we explored the possibility of removing the tissue by gene-directed enzyme prodrug th