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Prunustatin A, a Novel GRP78 Molecular Chaperone Down-regulator Isolated from Streptomyces violaceoniger

✍ Scribed by Umeda, Yukiko; Chijiwa, Shuhei; Furihata, Kazuo; Furihata, Keiko; Sakuda, Shohei; Nagasawa, Hiromichi; Watanabe, Hidenori; Shin-ya, Kazuo

Book ID: 111717532
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 95 KB
Volume: 58
Category: Article
ISSN: 0021-8820
DOI: 10.1038/ja.2005.25

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Prunustatin A, a Novel GRP78 Molecular C

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Absolute Structure of Prunustatin A, a N

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Versipelostatin, a novel GRP78/Bip molec

Versipelostatin, a novel GRP78/Bip molecular chaperone down-regulator of microbial origin

✍ Hae-Ryong Park; Kazuo Furihata; Yoichi Hayakawa; Kazuo Shin-ya 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 115 KB

We discovered a novel down-regulator of grp78 gene expression designated as versipelostatin from the culture broth of Streptomyces versipellis 4083-SVS6. Its structure was determined to be a macrocyclic compound consisting of an a-acyltetronic acid and sugar moieties.