Versipelostatin, a novel GRP78/Bip molecular chaperone down-regulator of microbial origin
β Scribed by Hae-Ryong Park; Kazuo Furihata; Yoichi Hayakawa; Kazuo Shin-ya
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 115 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
We discovered a novel down-regulator of grp78 gene expression designated as versipelostatin from the culture broth of Streptomyces versipellis 4083-SVS6. Its structure was determined to be a macrocyclic compound consisting of an a-acyltetronic acid and sugar moieties.
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