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Proximal nephron and renal effects of DuP 753, a nonpeptide angiotensin II receptor antagonist

โœ Scribed by Xie, Ming-Hong; Liu, Fu-Ying; Wong, Pancras C; Timmermans, Pieter B M W M; Cogan, Martin G


Book ID
109881574
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
646 KB
Volume
38
Category
Article
ISSN
0085-2538

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The uricosuric effect of DuP-753, a novel, specific angiotensin II receptor antagonist, has been explored in a healthy male Japanese volunteers, given single oral doses of 25, 50, 100 or 200 mg (n = 6), or 100 mg (n = 6) or placebo (n = 3) once daily for 7 consecutive days. In the single-dose study,