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Effect of a nonpeptide angiotensin II receptor antagonist, DuP 753, on angiotensin-related water intake in rats

โœ Scribed by Fregly, Melvin J.; Rowland, Neil E.


Book ID
123123086
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
519 KB
Volume
27
Category
Article
ISSN
0361-9230

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The uricosuric effect of DuP-753, a novel, specific angiotensin II receptor antagonist, has been explored in a healthy male Japanese volunteers, given single oral doses of 25, 50, 100 or 200 mg (n = 6), or 100 mg (n = 6) or placebo (n = 3) once daily for 7 consecutive days. In the single-dose study,