Protracted venous infusion 5-fluorouracil in combination with subcutaneous interleukin-2 and alpha-interferon in patients with metastatic renal cell cancer: a phase II study
โ Scribed by Allen, M.J.
- Book ID
- 119981064
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 69 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0007-0920
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๐ SIMILAR VOLUMES
## Abstract ## BACKGROUND The objective of this study was to determine the response rate and toxicity of gemcitabine and continuousโinfusion 5โfluorouracil (5โFU) in combination with subcutaneous interleukinโ2 (IL2) and interferonโฮฑ (IFNA) in patients with metastatic renal cell carcinoma. ## METH
## RESULTS. Fifty-five patients were enrolled in the trial and 52 were evaluable for ogy, The University of Texas M. D. Anderson response. All patients experienced fever and flu-like symptoms. Grade 3 or 4 nonhe-Cancer Center, Houston, Texas. matologic toxic effects included hypertension (48%), d