Protracted venous infusion 5-fluorouracil in combination with subcutaneous interleukin-2 and alpha-interferon in patients with metastatic renal cell cancer: a phase II study.
β Scribed by MJ Allen; M Vaughan; A Webb; S Johnston; P Savage; T Eisen; S Bates; J Morre; R Ahern; ME Gore
- Book ID
- 117724165
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 66 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1078-1439
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## RESULTS. Fifty-five patients were enrolled in the trial and 52 were evaluable for ogy, The University of Texas M. D. Anderson response. All patients experienced fever and flu-like symptoms. Grade 3 or 4 nonhe-Cancer Center, Houston, Texas. matologic toxic effects included hypertension (48%), d
## Abstract ## BACKGROUND The objective of this study was to determine the response rate and toxicity of gemcitabine and continuousβinfusion 5βfluorouracil (5βFU) in combination with subcutaneous interleukinβ2 (IL2) and interferonβΞ± (IFNA) in patients with metastatic renal cell carcinoma. ## METH