✦ LIBER ✦

Protothecosis after liver transplantation

✍ Scribed by Masashi Narita; Robert R. Muder; Thomas V. Cacciarelli; Nina Singh

Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 103 KB
Volume: 14
Category: Article
ISSN: 1527-6465
DOI: 10.1002/lt.21565

No coin nor oath required. For personal study only.

✦ Synopsis

Prototheca species are unicellular algae of low virulence that are rarely associated with human infections. We report a liver transplant recipient with disseminated protothecosis and review the literature on this unusual opportunistic infection in transplant recipients. Of 9 cases, including ours, 5 had a localized infection, and 4 had disseminated protothecosis. Seven cases were due to Prototheca wickerhamii, and 2 were due to Prototheca zopfii. Overall mortality in transplant recipients with Prototheca infections was 88% (7/8). All 4 cases of disseminated protothecosis died despite therapy with amphotericin B. Posttransplant protothecosis is a rare but significant infection that is associated with a grave prognosis.

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## Key Points 1. The goal of liver transplantation is not only to ensure the survival of patients but also to offer patients the opportunity to achieve a good balance between the functional efficacy of the graft and their psychological and physical integrity. The quality of life after transplantati