Proton magnetic resonance spectroscopy of the striatum in Parkinson's disease patients with motor response fluctuations
β Scribed by K.Ray Chaudhuri; G.M. Lemmens; S.C.R. Williams; C. Ellis; C.M. Lloyd; J. Dawson; A. Simmons; P.N. Leigh
- Book ID
- 116175215
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 528 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1353-8020
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π SIMILAR VOLUMES
Single voxel proton MRS was used to study brain metabolism in the striatum of patients diagnosed with idiopathic Parkinson's disease (PD). Peak metabolite ratios in long echo time spectra were evaluated in 151 patient spectra and 97 age-matched control spectra collected at four participating institu
## Abstract The objective of this study was to evaluate the efficacy, safety, and tolerability of istradefylline 20 mg once daily versus placebo as an adjunct to levodopa in subjects with Parkinson's disease (PD) who have motor fluctuations. Istradefylline (KWβ6002) is an adenosine A~2A~ receptor a