Application of proton magnetic resonance spectroscopy on substantia nigra metabolites in Parkinson’s disease
✍ Scribed by Zhou, Bing; Yuan, Fangzhen; He, Zhong; Tan, Changlian
- Book ID
- 121550101
- Publisher
- Springer-Verlag
- Year
- 2013
- Tongue
- English
- Weight
- 324 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1931-7557
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Purpose: To determine if tissue magnetic susceptibility is a more direct marker of tissue iron content than other MR markers of iron. This study presents the first quantitative, in vivo measurements of the susceptibility of the substantia nigra in patients with Parkinson's disease.
Proton magnetic resonance spectroscopy (1H-MRS), localized to the lentiform nucleus, was carried out in 12 patients with idiopathic Parkinson's disease (IPD), seven patients with multiple-system atrophy (MSA), seven patients with progressive supranuclear palsy (PSP), and 10 healthy age-matched contr